Intengo ye-Pregabalin CAS 148553-50-8
Incazelo Yomkhiqizo
Igama Lomkhiqizo: I-Pregabalin
INOMBOLO YE-CAS: 148553-50-8
Amagama afanayo:
i-3-(AminoMethyl)-5-Methyl-hexanoic acid;
(3S)-3-(Aminomethyl)-5-methylhexanoic acid;
Izakhiwo Zamakhemikhali Nezomzimba:
Ukubukeka: Okumhlophe kuya kokumhlophe qwa
Ukuhlolwa: ≥99.0%
Ubuningi: 0.997g/cm3
Indawo yokuncibilika: 194-196℃
Indawo Yokubilisa: 274℃ ku-760 mmHg
Iphuzu Lokukhanya: 119.5℃
Inkomba yokubuka: 1.464
Ukucindezela Komusi: 0.00153mmHg ku-25°C
I-PSA: 63.32000
I-LogP: 1.78240
Ukuncibilika: Kuncibilika kancane emanzini.
Isigaba: Imithi; I-API; Ama-Pfizer compounds; I-LYRICA;
Isicelo
I-S-Enantiomer ye-Pregabalin. I-analogue ye-GABA esetshenziswa njenge-anticonvulsant. I-Anxiolytic analgesic esetshenziselwa ukwelapha ubuhlungu be-peripheral neuropathic kanye ne-fibromyalgia.
I-Pregabalin uhlobo olusha lomuthi wokulwa nesifo sokuwa. Isakhiwo sayo sama-molecule sinesakhiwo se-gamma aminobutyric acid, ngakho-ke inemiphumela yokulwa nokuvuvukala. Yathuthukiswa ngempumelelo yi-Pfizer ukwelapha i-peripheral neuralgia noma ukwelashwa okungeziwe kokuwa okungaphelele. NgoDisemba 2008, i-US Food and Drug Administration (FDA) yavuma i-pregabalin yokwelapha i-diabetesic peripheral neuralgia (DPN) kanye ne-postherpetic neuralgia (PHN), ubuhlungu obubili obuvame kakhulu be-neuropathic. Ubuhlungu be-neuropathic bungenye yezinkinga ezinzima kakhulu zokwelapha ubuhlungu obungapheli. Bubonakala ngobuhlungu obungacacile, ukusha, nokuqaqamba. Kunezimbangela eziningi ze-neuralgia. Isifo sikashukela, izifo (ezifana ne-shingles), umdlavuza kanye ne-AIDS konke kungadala imizwa. Ubuhlungu, cishe abantu abangu-3% eYurophu bahlushwa yi-neuralgia.
Ukupakisha Nokugcina Izinto
Ukupakisha: 1kg/5kg/25kg noma ngokusekelwe kwisidingo sekhasimende.
Indawo Yokugcina: Igcinwa esitsheni esipholile nesomile esivalwe kahle. Gcina kude nomswakama nokukhanya/ukushisa okunamandla.
Imininingwane
Sicela usithumelele i-imeyili ukuze uthole i-COA.
