I-Mitoxantrone CAS: 65271-80-9 Ubumsulwa obungu-98%
Incazelo Yomkhiqizo
I-Mitoxantrone (i-Novantrone) iyi-anthraquinone yokwenziwa ehlobene ngokwesakhiwo nangokusebenza ne-anthracyclines. Ihlangana ne-DNA futhi idala ukuphuka kwe-DNA yomucu owodwa. Ayikwazi ukumelana ne-doxorubicin kumaseli amelana nemithi eminingi kanye nasezigulini ezihlulekile ukuphendula ekwelashweni kwe-doxorubicin.
I-Mitoxantrone iyasebenza ekulweni nomdlavuza webele, ama-leukemia, kanye nama-lymphoma. Ukusebenza kwayo ekulweni nomdlavuza webele kuphansi kancane kunokwe-doxorubicin. Ubuthi bayo obukhulu yi-myelosuppression; i-mucositis kanye nesifo sohudo nakho kungase kwenzeke. I-Mitoxantrone ikhiqiza isicanucanu esincane, i-alopecia, kanye nobuthi benhliziyo kune-doxorubicin.
Izakhiwo Zomkhiqizo
Igama Lomkhiqizo: Ama-API e-Mitoxantrone
Ukubukeka: Impuphu eluhlaza okwesibhakabhaka
Ukuncibilika: Kuncibilika kancane noma cishe akuncibiliki emanzini
Inombolo Yecala: 65271-80-9
Ifomula Yamamolekyuli: C22H28N4O6
Isisindo sama-molecule: 444.5 g/mol
Igama Lekhemikhali: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
Ukufaneleka ukuthunyelwa ngeposi njengempahla evamile: kufanelekile. Kuphephile ukuthunyelwa ngendiza njengempahla evamile.
Ubumsulwa noma Ukuhlolwa: 99%
Amazinga: Amazinga Amanje Ebhizinisi/e-USP
Izitifiketi ezitholakalayo: ISO
Imibhalo Etholakalayo: COA/MSDS
Amandla Okunikezela: 1KG ngenyanga
I-MOQ: 1 Gram
Isicelo
I-Mitoxantrone iyisidakamizwa esihlanganisa i-DNA. I-Mitoxantrone ivimbela ukwakheka kwe-DNA. I-Mitoxantrone isetshenziswa njenge-ejenti yokulwa nomdlavuza.
I-Mitoxantrone ingaba usizo ekwelapheni izifo eziningana ze-neoplastic ezinjeni nasemakatini, okuhlanganisa i-lymphosarcoma mammary adenocarcinoma, i-squamous cell carcinoma, i-renal adenocarcinoma, i-fibroid sarcoma, i-thyroid noma i-transitional cell carcinomas, kanye ne-hemangiopericytoma.
Ngenxa yokuthi ukuhlanzwa komuthi ezinso kuncane kakhulu (10%), unganikezwa amakati anokwehluleka kwezinso ngokuphephile kakhulu kune-doxorubicin.
Odokotela bayisebenzisela ukwelapha umdlavuza wendlala kanye nezinhlobo ezithile ze-leukemia.
Isebenza njenge-Topoisomerase Inhibitor.
Ukupakisha Nokugcina Izinto
Ukupakisha: 1g/5g/10g/100g ngephakheji ngayinye
Isitoreji: Gcina endaweni emnyama, Ivaliwe endaweni eyomile, 2-8°C
Imininingwane
| Igama | I-Mitoxantrone | ||
| I-CAS | 65271-80-9 | ||
| Izinto | Okujwayelekile | Imiphumela | |
| Ukubukeka | Impuphu eluhlaza okwesibhakabhaka | Ukuhambisana | |
| Ukuhlolwa, % | ≥99 | 99.1 | |
| Isiphetho | Abafanelekile | ||
