I-17α-Hydroxyprogesterone CAS 68-96-2

Isingeniso 17 α- I-Hydroxyprogesterone, ngezinye izikhathi ebizwa ngokuthi i-Hydroxyprogesterone (isiNgisi: i-hydroxyprogesterone, i-OHP), iyi-hormone ye-progesterone engaphandle efana ne-progesterone, futhi futhi iyisandulela se-biosynthesis yama-hormone amaningi e-steroid engaphandle, okuhlanganisa i-androgen, i-estrogen, i-glucocorticoid, i-mineralocorticoid kanye namanye ama-neurosteroids. I-Bioactive 17-Hydroxyprogesterone (17-OHP) iyi-progesterone engaphandle kanye nekhemikhali ephakathi kwe-biosynthesis yama-hormone e-steroid. Izifundo ze-in vitro 17 α-OHP iyi-agonist ye-chemobookin receptor efana ne-progesterone, yize umphumela wayo ubuthakathaka. Futhi iyi-chemical intermediate e-biosynthesis yama-hormone e-steroid njenge-androgens, i-estrogen, ama-hormone ocansi, ama-glucocorticoids, kanye ne-mineralocorticoids. Ucwaningo lwe-in vivo 17 I-Hydroxyprogesterone iyi-steroid inducer ephumelelayo ye-GVBD (ukuqhekeka kwe-vesicle yokuzala). Izakhiwo zamakhemikhali ukwakheka kwekristalu (i-acetone/hexane). Iphuzu lokuncibilika 221 ℃ (219-220 ℃). [α] 20/D+97 ° (chlorofor