I-17α-Hydroxyprogesterone CAS 68-96-2

Isingeniso 17 α- I-Hydroxyprogesterone, ngezinye izikhathi ebizwa ngokuthi i-Hydroxyprogesterone (isiNgisi: i-hydroxyprogesterone, i-OHP), iyi-progesterone steroid engapheli efana ne-progesterone, futhi iyisandulela se-biosynthesis yamahomoni amaningi e-endogenous steroid, okuhlanganisa i-androgen, i-estrogen, i-glucocorticoid, i-mineralocorticoid namanye ama-neurosteroids. I-Bioactive 17-Hydroxyprogesterone (17-OHP) iyi-progesterone engapheli kanye nekhemikhali emaphakathi ku-biosynthesis yamanye amahomoni e-steroid. Izifundo ze-in vitro ze-17 α- OHP iyi-progesterone efana ne-chemobookin receptor agonist, nakuba umphumela wayo ubuthakathaka. Kuphinde kube yikhemikhali emaphakathi ku-biosynthesis yamahomoni e-steroid afana ne-androgens, i-estrogen, amahomoni ocansi, i-glucocorticoids, ne-mineralocorticoids. Ucwaningo lwe-in vivo lwe-17 I-Hydroxyprogesterone iyi-steroid inducer esebenzayo ye-GVBD (ukuqhekeka kwe-vesicle yokuzala). I-crystallization yezakhiwo zamakhemikhali (i-acetone/hexane). Iphoyinti lokuncibilika 221 ℃ (219-220 ℃). [ α] 20/D+97 ° (chlorofor