17a-Hydroxyprogesterone CAS 68-96-2

Ifaara 17 α- Hydroxyprogesterone, nigbakan tọka si bi Hydroxyprogesterone (Gẹẹsi: hydroxyprogesterone, OHP), jẹ sitẹriọdu progesterone endogenous ti o jọra si progesterone, ati pe o tun jẹ aṣaaju ti biosynthesis ti ọpọlọpọ awọn homonu sitẹriọdu endogenous, pẹlu androgen, estrogen, glucocorticoid neurocorticoid, diẹ ninu awọn neurocorticoid neurocorticoid. Bioactive 17-Hydroxyprogesterone (17-OHP) jẹ progesterone endogenous ati agbedemeji kemikali ninu biosynthesis ti awọn homonu sitẹriọdu miiran. Awọn ẹkọ in vitro 17 α-OHP jẹ progesterone bi agonist olugba olugba chemobookin, botilẹjẹpe ipa rẹ jẹ alailagbara. O tun jẹ agbedemeji kemikali ninu biosynthesis ti awọn homonu sitẹriọdu bi androgens, estrogen, homonu ibalopo, glucocorticoids, ati mineralocorticoids. Ninu iwadi vivo 17 Hydroxyprogesterone jẹ inducer sitẹriọdu ti o munadoko fun GVBD (rupture vesicle ibisi). Awọn ohun-ini kemikali crystallization (acetone / hexane). Ojutu yo 221 ℃ (219-220 ℃). [α] 20/D+97 ° (chlorofor