I-Mitoxantrone CAS: 65271-80-9 Ubumsulwa obuyi-98%
Ingcaciso yeMveliso
I-Mitoxantrone (i-Novantrone) yi-anthraquinone eyenziweyo enxulumene ngokwesakhiwo nangokusebenza ne-anthracyclines. Idibana ne-DNA kwaye ivelisa ukwaphuka kwe-DNA yomcu omnye. Ayikwazi ukumelana ne-doxorubicin kwiiseli ezinganyangekiyo ngamayeza amaninzi nakwizigulane ezingakhange zikwazi ukuphendula kunyango lwe-doxorubicin.
I-Mitoxantrone iyasebenza kwi-breast carcinomas, i-leukemias, kunye ne-lymphomas. Ukusebenza kwayo ekulweni ne-tumor kwizigulana ezinomhlaza webele kuphantsi kancinci kune-doxorubicin. Ityhefu yayo enkulu yi-myelosuppression; i-mucositis kunye norhudo nazo zinokubakho. I-Mitoxantrone ivelisa isicaphucaphu esincinci, i-alopecia, kunye ne-cardiac toxicity kune-doxorubicin.
Iipropati zeMveliso
Igama leMveliso: ii-Mitoxantrone APIs
Inkangeleko: Umgubo oluhlaza okwesibhakabhaka omnyama
Ukunyibilika: Kunyibilika kancinci okanye phantse kunganyibiliki emanzini
Inombolo yeCas: 65271-80-9
Ifomula yeMolekyuli: C22H28N4O6
Ubunzima beMolekyuli: 444.5 g/mol
Igama leKhemikhali: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
Ukufaneleka ukuthunyelwa ngeposi njengempahla eqhelekileyo: kufanelekile. Kukhuselekile ukuthunyelwa ngenqwelo-moya njengempahla eqhelekileyo.
Ubumsulwa okanye Uvavanyo: 99%
Imigangatho: Imigangatho yangoku yeShishini/i-USP
Izatifikethi ezikhoyo: ISO
Amaxwebhu afumanekayo: COA/MSDS
Amandla okubonelela: 1KG ngenyanga
I-MOQ: 1 Gram
Isicelo
I-Mitoxantrone liyeza elidibanisa i-DNA. I-Mitoxantrone ithintela ukwenziwa kwe-DNA. I-Mitoxantrone isetyenziswa njengeyeza lokulwa nomhlaza.
I-Mitoxantrone inokuba luncedo ekunyangeni izifo ezininzi ze-neoplastic ezinjeni nakwiikati, kuquka i-lymphosarcoma mammary adenocarcinoma, i-squamous cell carcinoma, i-renal adenocarcinoma, i-fibroid sarcoma, i-thyroid okanye i-transitional cell carcinomas, kunye ne-hemangiopericytoma.
Ngenxa yokuba ukususwa kwesiyobisi kwizintso kuncinci (10%), singanikwa iikati ezinengxaki yezintso ngokukhuselekileyo kakhulu kunedoxorubicin.
Oogqirha bayisebenzisela ukunyanga umhlaza weprostate kunye neentlobo ezithile ze-leukemia.
Isebenza njengeTopoisomerase Inhibitor.
Ukupakisha kunye nokugcina
Ukupakisha: 1g/5g/10g/100g ngephakheji nganye
Indawo yokugcina: Gcina kwindawo emnyama, Ivalwe kwindawo eyomileyo, 2-8°C
Inkcazo
| Igama | I-Mitoxantrone | ||
| I-CAS | 65271-80-9 | ||
| Izinto | Umgangatho | Iziphumo | |
| Inkangeleko | Umgubo oluhlaza okwesibhakabhaka omnyama | Ukuhambelana | |
| Uvavanyo, % | ≥99 | 99.1 | |
| Isiphelo | Abafanelekileyo | ||
