I-17α-Hydroxyprogesterone CAS 68-96-2

Intshayelelo 17 α- IHydroxyprogesterone, ngamanye amaxesha ibizwa ngokuba yiHydroxyprogesterone (isiNgesi: i-hydroxyprogesterone, i-OHP), yiprogesterone steroid engapheliyo efana neprogesterone, kwaye ikwayi-precursor ye-biosynthesis yeehomoni ezininzi ze-endogenous steroid, ezibandakanya i-androgen, i-estrogen, i-glucocorticoid, i-mineralocorticoid kunye nezinye i-neurosteroids. I-Bioactive 17-Hydroxyprogesterone (17-OHP) yiprogesterone engapheliyo kunye nekhemikhali ephakathi kwi-biosynthesis yezinye iihomoni ze-steroid. Izifundo ze-in vitro i-17 α- OHP yiprogesterone efana ne-chemobookin receptor agonist, nangona umphumo wayo ubuthathaka. Ikwayikhemikhali ephakathi kwi-biosynthesis yeehomoni ze-steroid ezifana ne-androgens, i-estrogen, iihomoni zesini, i-glucocorticoids, kunye ne-mineralocorticoids. Kwisifundo se-vivo i-17 i-Hydroxyprogesterone yi-inducer ye-steroid esebenzayo ye-GVBD (i-reproductive vesicle rupture). Iipropati zeMichiza i-crystallization (i-acetone / i-hexane). Indawo yokunyibilika 221 ℃ (219-220 ℃). [ α] 20/D+97 ° (chlorofor