Mutengo wePregabalin CAS 148553-50-8
Tsananguro yeChigadzirwa
Zita rechigadzirwa: Pregabalin
Nhamba yeCAS: 148553-50-8
Mazwi akafanana:
3-(AminoMethyl)-5-Methyl-hexanoic acid;
(3S)-3-(Aminomethyl)-5-methylhexanoic acid;
Makemikari & Zvimiro zveMuviri:
Chitarisiko: Upfu huchena kusvika huchena
Kuyedza: ≥99.0%
Kuwanda: 0.997g/cm3
Nzvimbo yekunyunguduka: 194-196℃
Pokufashaira: 274℃ pa760 mmHg
Pokupenya: 119.5℃
Chiratidzo cheRefractive: 1.464
Kumanikidzwa kwemhepo: 0.00153mmHg pa25°C
PSA: 63.32000
LogP: 1.78240
Kunyungudika: Inonyungudika zvishoma mumvura.
Chikamu: Mishonga; API; Makomputa ePfizer; LYRICA;
Kushandiswa
S-Enantiomer yePregabalin. Mushonga weGABA unoshandiswa semushonga wekudzivirira pfari. Mushonga weAnxiolytic unoderedza marwadzo europi uye fibromyalgia.
Pregabalin imhando itsva yemushonga wekurwisa epileptic. Maumbirwo ayo emamorekuru ane chimiro che gamma aminobutyric acid, saka ine simba rekurwisa spasmodic. Yakagadzirwa zvinobudirira nePfizer kurapa peripheral neuralgia kana kurapa kwekuwedzera kwechirwere chepfungwa. Muna Zvita 2008, US Food and Drug Administration (FDA) yakabvumidza pregabalin kurapa chirwere cheshuga peripheral neuralgia (DPN) uye postherpetic neuralgia (PHN), marwadzo maviri anowanzo shandiswa neuropathic. Marwadzo e neuropathic ndeimwe yemarwadzo akaoma kurapa chronic pain syndromes. Inoratidzwa nekurwadziwa kusingafadzi, kupisa, uye kukwenya. Kune zvikonzero zvakawanda zve neuralgia. Chirwere cheshuga, hutachiona (senge shingles), kenza neAIDS zvese zvinogona kukonzera tsinga. Marwadzo, vanhu vanosvika 3% muEurope vanotambura ne neuralgia.
Kurongedza & Kuchengeta
Kurongedza: 1kg/5kg/25kg kana zvichienderana nezvinodiwa nemutengi.
Kuchengetera: Inochengetwa mumudziyo unotonhorera uye wakaoma wakavharwa zvakanaka. Chengeta kure nehunyoro uye chiedza chakasimba/kupisa.
Tsanangudzo
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