Igiciro cya Pregabalin CAS 148553-50-8
Ibisobanuro by'igicuruzwa
Izina ry'igicuruzwa: Pregabalin
INOMERO Y'IBIHE: 148553-50-8
Amagambo asa:
3- (AminoMethyl)-5-Methyl-hexanoic aside;
(3S)-3- (Aminomethyl)-5-aside hexanoic;
Imiterere y'ibinyabutabire n'ibifatika:
Ishusho: Ifu y'umweru kuva ku ifu y'umweru
Isuzuma: ≥99.0%
Ubucucike: 0.997g/cm3
Aho gushonga: 194-196℃
Aho kubira: 274℃ kuri 760 mmHg
Aho ubushyuhe bugera: 119.5℃
Igipimo cy'ikirahure: 1.464
Umuvuduko w'umwuka: 0.00153mmHg kuri 25°C
PSA: 63.32000
LogP: 1.78240
Gushonga: Bishongera gushonga mu mazi.
Icyiciro: Imiti; API; Ibinyabutabire bya Pfizer; LYRICA;
Porogaramu
S-Enantiomer ya Pregabalin. Ni umuti ugabanya ububabare mu mitsi. Umuti ugabanya ububabare mu mitsi ukoreshwa mu kuvura ububabare bw'imitsi yo mu mpande na fibromyalgia.
Pregabalin ni ubwoko bushya bw'umuti urwanya igicuri. Imiterere yawo ya molekile ifite imiterere ya aside ya gamma aminobutyric, bityo ikaba ifite ingaruka zo kurwanya spasmodic. Yakozwe neza na Pfizer kugira ngo ivure neuralgia yo mu gice cy'umubiri cyangwa kuvura indwara z'ibicurane. Mu Kuboza 2008, Ikigo gishinzwe ibiribwa n'imiti muri Amerika (FDA) cyemeje pregabalin mu kuvura diyabete peripheral neuralgia (DPN) na neuralgia yo mu gice cy'umubiri (PHN), ububabare bubiri bukunze kugaragara cyane mu mitsi. Ububabare bwo mu mutwe ni bumwe mu bubabare bugoye kuvura. Burangwa no kubabara buhoro, gushya, no kuribwa. Hari impamvu nyinshi zitera neuralgia. Diyabete, indwara zandurira mu mubiri (nk'ibishishi), kanseri na SIDA byose bishobora gutera imitsi. Ububabare, abantu bagera kuri 3% mu Burayi barwaye neuralgia.
Gupakira no Kubika
Gupakira: 1kg/5kg/25kg cyangwa hashingiwe ku byo umukiriya akeneye.
Kubika: Bibikwa mu gikoresho gikonje kandi cyumye kandi gifunze neza. Bika kure y'ubushuhe n'urumuri rwinshi/ubushyuhe.
Ibisobanuro
Nyamuneka tundikire kuri imeri kugira ngo ubone COA.
