Igiciro cya Medroxyprogesterone Acetate CAS 71-58-9

Medroxyprogesterone Acetate, izwi kandi nka Medroxyprogesterone 17-acetate cyangwa MPA, ni progestogen y’ubukorano na progestin ya steroidal. Ikomoka kuri progesterone y’umuntu. Ibuza intanga no kongera umuvuduko w’ingendo z’amagi ziva mu miyoboro y’inda zigera muri nyababyeyi mu mabere y’ingore iyo zitanzwe mbere yo gusohora intanga. Medroxyprogesterone 17-acetate ibuza intanga gusohora intanga mu mbeba iyo zitewe ku munsi wa nyuma w’imisemburo. Ifite kandi imikorere yo kurwanya androgenic mu mbeba, igabanya urugero rwa testosterone mu maraso binyuze mu gutuma testosterone reductase ikorwa mu mwijima. Medroxyprogesterone 17-acetate igira ingaruka zo kugabanya ubudahangarwa bw’umubiri mu mubiri no mu mubiri, ikabuza ikorwa rya IFN-γ na CD2/CD3/CD28-stimulated peripheral blood mononuclear cells (PBMCs) ku gipimo cya ≥10 nM kandi yongerera ubuzima bw’udukoko tw’uruhu rw’urukwavu. Imiti iterwa irimo medroxyprogesterone 17-acetate yakoreshejwe nk'imiti yo kuboneza urubyaro.