Mtengo wa Pregabalin CAS 148553-50-8

S-Enantiomer ya Pregabalin. Mankhwala ofanana ndi a GABA omwe amagwiritsidwa ntchito ngati mankhwala oletsa kupweteka kwa mutu. Mankhwala ochepetsa nkhawa omwe amagwiritsidwa ntchito pochiza ululu wa mitsempha ndi fibromyalgia.

Pregabalin ndi mtundu watsopano wa mankhwala oletsa khunyu. Kapangidwe kake ka molekyulu kali ndi kapangidwe ka gamma aminobutyric acid, kotero kali ndi mphamvu zoletsa kutsekeka kwa mitsempha. Pfizer idapangidwa bwino kuti ichite neuralgia ya m'mphepete kapena chithandizo chothandizira cha khunyu. Mu Disembala 2008, US Food and Drug Administration (FDA) idavomereza pregabalin kuti ichite neuralgia ya matenda a shuga (DPN) ndi neuralgia ya pambuyo pa herpetic (PHN), ululu wachiwiri wofala kwambiri wa neuropathic. Kupweteka kwa neuropathic ndi chimodzi mwazovuta kwambiri kuchiza matenda opweteka osatha. Kumadziwika ndi kupweteka kosawoneka bwino, kutentha, ndi kumva kuwawa. Pali zifukwa zambiri za neuralgia. Matenda a shuga, matenda (monga shingles), khansa ndi Edzi zonse zimatha kuyambitsa mitsempha. Kupweteka, pafupifupi 3% ya anthu ku Europe amadwala neuralgia.