Te utu mō te Medroxyprogesterone Acetate CAS 71-58-9

Ko te Medroxyprogesterone Acetate, e mōhiotia ana ko te Medroxyprogesterone 17-acetate, MPA rānei, he progestogen hangai me te progestin steroidal. I ahu mai i te homoni tangata progesterone. Ka ārai i te whakamomona, ā, ka tere ake te kawe i ngā hua manu mai i ngā ngongo fallopian ki te kōpū i roto i ngā ferret uwha ina tukuna i mua i te whakaputanga o te hua manu. Ka ārai anō te Medroxyprogesterone 17-acetate i te whakaputanga o te hua manu i roto i ngā kiore ina werohia i te rā whakamutunga o te diestrus. He mahi anti-androgenic anō hoki i roto i ngā kiore, ka whakaiti i ngā taumata testosterone plasma mā te whakaoho i te mahi testosterone reductase ate. Ka whakaatuhia e te Medroxyprogesterone 17-acetate ngā pānga ārai mate i roto i te vitro me te in vivo, ka aukati i te hanga IFN-γ e ngā pūtau mononuclear toto peripheral stimulated CD2/CD3/CD28 (PBMCs) i ngā kukū ≥10 nM me te whakaroa i te oranga o ngā allografts kiri rāpeti. Kua whakamahia ngā werohanga kei roto ko te medroxyprogesterone 17-acetate hei ārai hapūtanga.