Povidone Iodine CAS 25655-41-8
Povidone iodine yog ib qho complex ntawm povidone K30 nrog iodine, uas muaj zog tua cov kab mob, kab mob, fungi, pwm thiab spores. Ruaj khov, tsis ua mob, ua kom dej soluble.
Yam khoom
Lub npe Pharmacopoeia:Povidone Iodine, Povidone-Iodine (USP), Povidone-Iodinated (EP)
Lub npe tshuaj: complex ntawm polyvinylpyrrolidone nrog iodine
Khoom npe:Povidone Iodine
Cas No.: 25655-41-8; 74500-22-4 : kuv
Molecular Luj: 364.9507
Cov mis mos molecular: C6H9I2NO
Mechanism ntawm kev txiav txim: PVP yog ib tug hydrophilic polymer uas tsis muaj antibacterial nyhuv. Txawm li cas los xij, vim nws txoj kev sib raug zoo rau cov cell membranes, nws tuaj yeem ncaj qha coj iodine mus rau lub cell ntawm cov kab mob, uas muaj qhov tseem ceeb rau kev txhim kho cov tshuaj tua kab mob ntawm iodine. Lub hom phiaj ntawm iodine yog cov kab mob cytoplasm thiab cytoplasmic membrane, uas tua cov kab mob tam sim ntawd hauv ib lub vib nas this. Thaum cov molecules tsim nyog rau kev ciaj sia ntawm cov kab mob xws li sulfhydryl compounds, peptides, proteins, lipids thiab cytosine raug tiv tauj nrog PVP-I, lawv tam sim ntawd oxidized los yog iodinated los ntawm iodine kom poob lawv cov dej num thiab ua tiav cov kab mob mus ntev.
Povidone iodine yog ib qho complex ntawm iodine nrog povidone. Nws tshwm sim raws li ib tug yellowish xim av rau reddish xim av amorphous hmoov, muaj ib tug me ntsis yam ntxwv tsw. Nws cov tshuaj yog acid rau litmus. Soluble nyob rau hauv dej thiab cawv, xyaum insoluble nyob rau hauv chloroform, nyob rau hauv carbon tetrachloride, nyob rau hauv ether, nyob rau hauv hnyav hexane, thiab nyob rau hauv acetone. Nws yog ib qho tshuaj tua kab mob sab nraud nrog dav microbicidal spectrum tiv thaiv kab mob, fungi, kab mob, protozoa, thiab poov xab. Cov gel no muaj li ntawm 1.0% muaj iodine.
Txuj kev zoo
| Pharmacopoeia standard | Qhov tshwm sim | Cov txiaj ntsig iodine /% | Residue ntawm ignition /% | Poob ntawm ziab /% | Iodine ion /% | Arsenic ntsev / ppm | Heavy hlau / ppm | Nitrogen cov ntsiab lus /% | PH tus nqi (10% aqueous tov) |
| PIB 2010 | Reddish xim av mus rau daj xim av amorphous hmoov | 9.0-12.0 Nws | ≤0.1 | ≤8.0 | ≤6.6 | ≤1.5 | ≤ 20 | 9.5-11.5 Nws | / |
| USP32 | ≤ 0.025 | ≤8.0 | ≤6.6 | / | ≤ 20 | 9.5-11.5 Nws | / | ||
| EP 7.0 | ≤0.1 | ≤8.0 | ≤ 6.0 | / | / | / | 1.5-5.0 Nws |
Siv tau iodine 20% (tus qauv lag luam)
| Qhov tshwm sim | Cov txiaj ntsig iodine /% | Residue ntawm ignition /% | Poob ntawm ziab /% | Iodine ion /% | Arsenic ntsev / ppm | Heavy hlau / ppm | Nitrogen cov ntsiab lus /% |
| Reddish xim av mus rau daj xim av amorphous hmoov | 18.5-21.0 Nws | ≤0.1 | ≤8.0 | ≤13.5 | ≤1.5 | ≤ 20 | 8.0-11.0 Nws |
Cov lus qhia tseem ceeb ntawm Povidone iodine yog raws li hauv qab no:
1. nws tuaj yeem siv rau kev kho mob suppurative dermatitis, fungal kab mob ntawm daim tawv nqaij, thiab qhov chaw me me ntawm qhov kub hnyiab; kuj tuaj yeem siv rau kev tua kab mob ntawm thaj chaw me me ntawm daim tawv nqaij thiab cov mucous membrane qhov txhab.
2. Nws tuaj yeem siv rau kev tiv thaiv thiab tshuaj tua kab mob tropic ntawm ntau yam kab mob xws li kab mob thiab pwm vaginitis, cervical erosion, trichomonas vaginitis, qhov chaw mos khaus, tsis hnov tsw ntawm qhov chaw mos, daj thiab tsis hnov tsw leucorrhea, dav qhov chaw mos o, laus vaginitis, herpes, gout.
3. Nws tuaj yeem siv rau kev kho mob glans o, posthitis, thiab tshuaj tua kab mob ntawm qhov chaw mos thiab thaj chaw ib puag ncig. Kuj tseem siv rau kev tiv thaiv thiab kev kho mob kub thiab tshuaj tua kab mob gonorrhea, syphilis, thiab qhov chaw mos warts.
4. nws tuaj yeem siv rau kev tua kab mob ntawm cutlery thiab tableware.
5. nws tuaj yeem siv los yog tshuaj tua kab mob ntawm daim tawv nqaij.
25KG / cardboard nruas, kaw, khaws cia rau hauv qhov chaw txias qhuav thiab tsaus.
