ʻO ke kumukūʻai o Pregabalin CAS 148553-50-8
Wehewehe Huahana
Inoa Huahana: Pregabalin
CAS NO:148553-50-8
Nā huaʻōlelo like:
ʻAkika 3-(AminoMethyl)-5-Methyl-hexanoic;
ʻakika (3S)-3-(Aminomethyl)-5-methylhexanoic;
Nā Waiwai Kemika a me ke Kino:
ʻAno: Pauka keʻokeʻo a keʻokeʻo paha
Hoʻāʻo: ≥99.0%
Ka nui o ke kaumaha: 0.997g/cm3
Kiko heheʻe: 194-196 ℃
Kikowaena paila: 274 ℃ ma 760 mmHg
Kikowaena Uila: 119.5 ℃
ʻIke kuhikuhi refractive: 1.464
Kaomi mahu: 0.00153mmHg ma 25°C
PSA: 63.32000
LogP: 1.78240
Ka hoʻoheheʻe ʻia: Hoʻoheheʻe iki ʻia i ka wai.
Māhele: Nā lāʻau lapaʻau; API; Nā hui Pfizer; LYRICA;
Noi
S-Enantiomer o Pregabalin. He analogue GABA i hoʻohana ʻia ma ke ʻano he anticonvulsant. Analgesic anxiolytic i hoʻohana ʻia e mālama i ka ʻeha neuropathic peripheral a me ka fibromyalgia.
He ʻano lāʻau anti-epileptic hou ʻo Pregabalin. Loaʻa i kona ʻano molekala kahi ʻano gamma aminobutyric acid, no laila he hopena anti-spasmodic. Ua hoʻomohala kūleʻa ʻia e Pfizer e mālama i ka neuralgia peripheral a i ʻole ka mālama adjuvant o nā hopu hapa. . I Dekemaba 2008, ua ʻae ka US Food and Drug Administration (FDA) i ka pregabalin no ka mālama ʻana i ka neuralgia peripheral diabetic (DPN) a me ka postherpetic neuralgia (PHN), ʻo ia nā ʻeha neuropathic ʻelua maʻamau. ʻO ka ʻeha neuropathic kekahi o nā mea paʻakikī loa e mālama i nā syndromes ʻeha mau. Hōʻike ʻia ia e ka ʻeha ʻole, ka wela, a me ke kani ʻana. Nui nā kumu o ka neuralgia. ʻO ka maʻi diabetes, nā maʻi (e like me ka shingles), ke kanesa a me ka AIDS hiki ke hoʻoulu i nā aʻalolo. ʻO ka ʻeha, ma kahi o 3% o ka poʻe ma ʻEulopa e ʻeha nei i ka neuralgia.
Hoʻopili a me ka mālama ʻana
Hoʻopili ʻana: 1kg/5kg/25kg a i ʻole ma muli o ke koi a ka mea kūʻai aku.
Ka Mālama ʻana: Mālama ʻia i loko o kahi pahu anu a maloʻo a pani pono ʻia. E mālama ʻia mai ka makū a me ka mālamalama/wela ikaika.
Nā kikoʻī
E ʻoluʻolu e leka uila mai iā mākou e kiʻi i ka COA.
