17α-Hydroxyprogesterone CAS 68-96-2

Ro-ràdh 17 α- Hydroxyprogesterone, ris an canar uaireannan Hydroxyprogesterone (Beurla: hydroxyprogesterone, OHP), na steroid progesterone endogenous coltach ri progesterone, agus tha e cuideachd na ro-ruithear airson bith-cho-chur mòran hormonaichean steroid endogenous, nam measg androgen, estrogen, glucocorticoid, mineralocorticoid agus cuid de neurosteroids. Tha 17-Hydroxyprogesterone (17-OHP) bith-ghnìomhach na progesterone endogenous agus na eadar-mheadhanair ceimigeach ann am bith-cho-chur hormonaichean steroid eile. Sgrùdaidhean in vitro Tha 17 α-OHP na agonist gabhadair chemobookin coltach ri progesterone, ged a tha a bhuaidh an ìre mhath lag. Tha e cuideachd na eadar-mheadhanair ceimigeach ann am bith-cho-chur hormonaichean steroid leithid androgens, estrogen, hormonaichean gnè, glucocorticoids, agus mineralocorticoids. Sgrùdadh in vivo 17 Tha Hydroxyprogesterone na bhrosnachadh steroid èifeachdach airson GVBD (briseadh vesicle gintinn). Feartan ceimigeach criostalachadh (acetone / hexane). Puing leaghaidh 221 ℃ (219-220 ℃). [α] 20/D+97 ° (clòrofòr